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New Phase I Clinical Trial for HIV+ Individuals Who Are Undetectable

We are looking for HIV+ people who are taking antiretroviral treatment (ART) and whose viral load is undetectable. The goal is to find out if IL-15 is safe alone, or when used in combination with another treatment called broadly neutralizing antibodies (bNAbs). Participants will receive 8 doses of IL-15 given every 3 weeks. Half of the IL-15 participants will be randomly assigned to also receive the bNAbs with it. After completing these treatments, participants will temporarily stop taking their HIV medicine (ART) and will be evaluated to see how well this treatment controls their viral load.

 

Basic eligibility criteria:

  • Age 18 to 65 years old
  • HIV positive
  • On continuous HIV treatment (antiretroviral therapy) for at least 52 weeks
  • Undetectable HIV viral load for at least 52 weeks
  • CD4 cell count more than 450
  • No active Hepatitis B or C infection
  • Not pregnant or breastfeeding

 

Principal Investigator: Kara Chew, MD, MSc

 

For more information contact the UCLA study team at (310) 843-2015 or CAREOutreach@mednet.ucla.edu

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