UCLA/Orthopaedic Hospital Department of Orthopaedic Surgery and UCLA’s Institute of Pure and Applied Mathematics (IPAM) announce The first workshop on Bone Tissue: Hierarchical Simulations for Clinical Applications (BTHSCA1) April 21-23, 2010 at UCLA Call for Abstracts BTHSCA1 aims to bring together orthopaedic surgeons, clinicians, bone and system biologists, mechanical and software engineers, and applied mathematicians to share the latest findings and formulate a plan to develop the next generation of three-dimensional multi-scale virtual rendering of bone tissue able to address specific clinical issues. The need for this workshop is based on
• the increasing evidence that bone shows a plethora of divergent characteristics through a hierarchically-organized heterogeneous structure that varies across nano- micro- , and macro- length scales; and
• the highly interdisciplinary nature of hierarchical modeling, based on developments that occur independently across multiple scientific disciplines and address phenomena manifested at the different scales. We offer up to 21 CMEs The CME participants will learn to: • describe the known role of nano- and micro- structure in bone macro-mechanics;
• examine the (potential) bone tissue parameters of fracture risk; and
• assess the various imaging technologies for bone.
Keynote Speakers David Burr, Professor, Department of Anatomy and Cell Biology and Department of Orthopaedic Surgery Indiana University School of Medicine, Department of Biomedical Engineering IUPUI and Purdue University Research Interests: Effects of pharmacologic treatments of osteoporosis; microdamage; quality of bone matrix (website)
Marjolein van der Meulen, Professor, Mechanical and Aerospace Engineering, Cornell University Research Interests: bone tissue mechanics; determinants of skeletal mechanical behavior; bone adaptation to mechanical stimuli ( website)
Nico Verdonschot, Professor, Implant Biomechanics, Radboud University Nijmegen Medical Centre, The Netherlands & University of Twente, Enschede, The Netherlands Research Interests: Micro- and macro- failure analyses of orthopaedic implants; focus on bone cement and the interfaces (stem-cement and cement-bone); finite element methods (website)
Reception On Thursday night, UCLA’s Institute of Pure and Applied Mathematics (IPAM) will sponsor a reception on campus. Organizing Committee Maria-Grazia Ascenzi, PhD in Mathematics UCLA/Orthopedic Hospital Department of Orthopaedic Surgery mgascenzi@mednet.ucla.edu (website)
John S. Adams, MD UCLA/Orthopedic Hospital Department of Orthopaedic Surgery (website)
Elena Cherkaev, PhD in Mathematics Department of Mathematics, University of Utah (website)
Paul C. Dechow, PhD in Anatomy Department of Biomedical Sciences, Texas A&M Health Science Center Baylor College of Dentistry(website)
Eve Donnelly, PhD in Mechanical Engineering Mineralized Tissues Laboratory, Hospital for Special Surgery (website)
Gwendolen Reilly, PhD in Biology Engineering Materials, University of Sheffield, United Kingdom (webite)
Workshop Topics
•EFFECT OF BONE PATHOLOGY ON MACRO AND/OR MICRO- AND/OR NANO-SCALE STRUCTURE
•MULTISCALE APPROACHES TO CLINICAL ISSUES
•CLINICAL ALTERATIONS OF MICRO- AND/OR NANO- SCALE STRUCTURE
•MULTISCALE PARAMETERS OF BONE TISSUE QUALITY
•SCALE TRANSITION IN BONE SIMULATION
•FRACTURE PREDICTION IN MULTISCALE SYSTEMS
•DATA COLLECTION AT NANO-, MICRO-, OR MACRO- LEVEL FOR BONE SIMULATION
•MANAGEMENT OF LARGE DATA SETS •PATTERN RECOGNITION AND/OR DATA MINING IN COLLECTED DATA •BIOLOGICAL VARIATION OF DATA IN STATISTICAL TERMS: WHAT DOES “NORMAL” MEAN?
•EXPERIMENTAL DESIGN FOR SPECIFIC MODELING PURPOSES
•THE MATHEMATICS OF THE INTERACTION OF BONE TISSUE’S COMPONENTS
•ADHERENCE OF MODELING TO EXPERIMENTAL FINDINGS
•SOFTWARE DESIGN FOR IMPLEMENTATION OF ENGINEERING SIMULATION
•INTERACTIONS BETWEEN NON-BIOLOGICAL MATERIALS AND BONE TISSUE
•SUPER-COMPUTING RESOURCES FOR COMPLEX MODELING Residents and junior investigators, and women, underrepresented minorities and individuals with disabilities are encouraged to apply: scholarships will be awarded to the first author of the nine most meritorious abstracts. Important Deadlines Registration Opens October 13, 2009
Abstract Submission Closes December 1, 2009
Notification of Acceptance January 1, 2010
Early Registration Ends January 15, 2010
Housing Closes March 20, 2010
To submit abstract and/or register: click here
Abstract Requirements Length: one page containing one image; Margins: 0.5in; Font: Arial 11pt; Content : Title, authors with institutions, introduction, methods, results, references (optional), at least one workshop topic, contact information of first author including email address, whether a resident, junior investigator (within five years from a PhD), woman, underrepresented minority, person with disability.
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